Abstract
Limnophilaplants  show  numerous  medicinal  applications  in  the  traditional  system.  The  plants  are  reported  to exhibit significant antimicrobial activity. The present study was carried out to investigate phytochemical compositions and antibacterial activities of Limnophila rugosa(Roth) Merr. Methanol, ethanol and water crude extracts of L. rugosaleaves were  evaluated for  total  phenolic contents, flavonoid, -carotene and  lycopene. The  study revealed  that the  alcoholic extracts  obtained  significantly  higher  total  phenolic  contents,  flavonoid, carotene  and  lycopene  than  distilled  water extracts.Aqueous and alcoholic extracts were investigated for antibacterial activity by agar well diffusion method against Staphylococcus aureus, Escherichia coli, Bacillus subtilis  and  Vibrio cholerae . All strains showed similar sensitivity of aqueous  and alcoholic extracts of  L. rugosa leaves with clear zone area about  0.7 ±0.00 – 1.4 ±0.71 cm. However, it was founded that  ethanol crude extract of the plant had high tendency to inhibitory against  S. aureus with MIC and MBC value of 12.5 and 100  mg/ml,  respectively. The  extract  was  found to  effective against  gram  positive and  gram  negative bacteria.  It  can be
phytochemical-and-antibacterial-studies-of-the-crude-leaves-extract-from-limnophila-rugosa-roth-merr