Limnophilaplants show numerous medicinal applications in the traditional system. The plants are reported to exhibit significant antimicrobial activity. The present study was carried out to investigate phytochemical compositions and antibacterial activities of Limnophila rugosa(Roth) Merr. Methanol, ethanol and water crude extracts of L. rugosaleaves were evaluated for total phenolic contents, flavonoid, -carotene and lycopene. The study revealed that the alcoholic extracts obtained significantly higher total phenolic contents, flavonoid, carotene and lycopene than distilled water extracts.Aqueous and alcoholic extracts were investigated for antibacterial activity by agar well diffusion method against Staphylococcus aureus, Escherichia coli, Bacillus subtilis and Vibrio cholerae . All strains showed similar sensitivity of aqueous and alcoholic extracts of L. rugosa leaves with clear zone area about 0.7 ±0.00 – 1.4 ±0.71 cm. However, it was founded that ethanol crude extract of the plant had high tendency to inhibitory against S. aureus with MIC and MBC value of 12.5 and 100 mg/ml, respectively. The extract was found to effective against gram positive and gram negative bacteria. It can be
phytochemical-and-antibacterial-studies-of-the-crude-leaves-extract-from-limnophila-rugosa-roth-merr